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CD4+ Th cell subsets in fungal infections.
| Th cells | Cytokines | Functions | |
|---|---|---|---|
 |
Th1 | IFN-γ/TNF-α | Fungal clearance |
| Inflammation | |||
|
Th17 | IL-17A/IL-17F | Defensins, neutrophil recruitment |
| Inflammation | |||
|
Th22 | IL-22 | Defensins |
| Tissue homeostasis | |||
 |
Th2 | IL-4/IL-13 | Humoral response |
| Allergy | |||
|
Th9 | IL-9/IL-10 | Tissue inflammation |
 |
Treg | IL-10/TGF-β | Low inflammation |
| Immunosuppression | |||
|
Tr1 | IL-10 | Low immunopathology |
