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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Ophthalmology. 2014 Mar 27;121(7):1389–1397. doi: 10.1016/j.ophtha.2014.01.033

Figure 5.

Figure 5

Reduced thrombospondin 1 (TSP-1) levels and increased inflammation are detectable in single nucleotide polymorphisms (SNP1) minor allele carriers. RNA was harvested from conjunctival impression cytology samples and analyzed using SYBR Green (Applied Biosystems, Carlsbad, CA) real-time polymerase chain reaction assay to determine levels of TSP-1 (A) and interleukin (IL)-1β (B). Expression of TSP-1 in SNP1 minor allele carriers (CC+CT) compared with the major genotype (TT) was significantly reduced, whereas expression of inflammatory cytokine IL-1β was significantly increased. *P < 0.05.