Table 2.
Wild-type intestine 3' UTR Apobec-1 RNA targets (>30% editing efficiency)
| RNA | Chr | Position | Reference base | RNA-seq | Reads | Sanger | Edited/total | |
|---|---|---|---|---|---|---|---|---|
| 1. |
Cd36 |
5 |
17288955 (-) |
G |
84% |
44 |
85% |
(17/20) |
| 2. |
Reps2 |
X |
158851906 (-) |
G |
75% |
12 |
50% |
(10/20) |
| 3. |
Siglec5 |
7 |
50614573 (+) |
C |
72% |
43 |
10% |
(2/20) |
| 4. |
Fmn1 |
2 |
113556683 (+) |
C |
71% |
17 |
65% |
(13/20) |
| 5. |
0610010O12Rik |
18 |
36562329 (+) |
C |
67% |
2900 |
55% |
(11/20) |
| 6. |
Mcmbp |
7 |
135841366 (-) |
G |
63% |
155 |
30% |
(7/23) |
| 7. |
Man2a1 |
17 |
65104330 (+) |
C |
60% |
119 |
15% |
(3/20) |
| 8. |
Herc2 |
7 |
63486942 (+) |
C |
60% |
15 |
5% |
(1/20) |
| 9. |
Ddx60 |
8 |
64516163 (+) |
C |
59% |
22 |
30% |
(6/20) |
| 10. |
Tmem195 |
12 |
38308269 (+) |
C |
56% |
466 |
44% |
(11/25) |
| 11. |
Mtmr2 |
9 |
13610423 (+) |
C |
53% |
19 |
25% |
(5/20) |
| 12. |
Cyp2c65 |
19 |
39168358 (+) |
C |
50% |
1011 |
9.5% |
(2/21) |
| 13 |
Cnih |
14 |
47395982 (-) |
G |
48% |
25 |
59% |
(13/22) |
| 14. |
Atp11c |
X |
57477477 (-) |
G |
46% |
13 |
5% |
(1/19) |
| 15. |
Sh3bgrl |
X |
106356686 (+) |
C |
45% |
83 |
35% |
(7/20) |
| 16. |
Fgl2 |
5 |
20883372 (+) |
C |
42% |
72 |
33% |
(7/21) |
| 17. |
Nr1d2 |
14 |
19036726 (-) |
G |
39% |
82 |
25% |
(5/20) |
| 18. |
Tmem135 |
7 |
96290044 (-) |
G |
39% |
28 |
20% |
(4/20) |
| 19. |
Slc4a4 |
5 |
89668527 (+) |
C |
38% |
21 |
45% |
(9/20) |
| 20. |
Dpyd |
3 |
119134696 (+) |
C |
38% |
66 |
25% |
(5/20) |
| 21. |
Ttc9c |
19 |
8885447 (-) |
G |
37% |
16 |
18% |
(4/22) |
| 22. |
Yes1 |
5 |
32989151 (+) |
C |
36% |
22 |
30% |
(6/20) |
| 23. |
1110020G09Rik |
15 |
9038469 (+) |
C |
36% |
22 |
10% |
(2/20) |
| 24. |
Actr2 |
11 |
19963383 (-) |
G |
35% |
52 |
41% |
(9/22) |
| 25. |
Kctd12 |
14 |
103379573 (-) |
G |
35% |
63 |
28% |
(5/18) |
| 26. |
Nr3c1 |
18 |
39571801 (-) |
G |
33% |
18 |
17% |
(4/24) |
| 27. |
Skil |
3 |
31018375 (+) |
C |
33% |
16 |
5% |
(1/20) |
| 28. |
Ccny |
18 |
9315769 (-) |
G |
32% |
25 |
25% |
(5/20) |
| 29. |
Rab1 |
11 |
20125336 (+) |
C |
32% |
508 |
15% |
(3/20) |
| 30. |
mCG_2776 |
6 |
8378189 (+) |
C |
31% |
36 |
20% |
(4/20) |
| 31. |
Lrba |
4 |
9503468 (+) |
C |
31% |
37 |
6% |
(1/16) |
| 32. | Dek | 13 | 47181166 (-) | G | 31% | 26 | 5% | (1/20) |
(+) Sense strand.
(-) Antisense strand.