Table 3.
Wild-type liver 3’ UTR Apobec-1 RNA targets
RNA | Chr | Position | Reference base | RNA-seq | Reads | Sanger | Edited/total | |
---|---|---|---|---|---|---|---|---|
1. |
Serinc1 |
10 |
57235791 (-) |
G |
38% |
186 |
9.5% |
(2/21) |
2. |
Dcn* |
10 |
96980667 (+) |
C |
30% |
104 |
14% |
(3/21) |
|
Dcn* |
10 |
96980535 (+) |
C |
14% |
370 |
14% |
(3/21) |
3. |
Cd36 |
5 |
17288955 (-) |
G |
24% |
45 |
23% |
(5/21) |
4. |
Cybb* |
X |
9012717 (-) |
G |
23% |
13 |
18% |
(4/22) |
|
Cybb* |
X |
9012852 (-) |
G |
23% |
13 |
4.5% |
(1/22) |
|
Cybb* |
X |
9013390 (-) |
G |
14% |
21 |
14% |
(2/16) |
5. |
Colec10* |
15 |
54297696 (+) |
C |
18% |
17 |
5% |
(1/20) |
|
Colec10* |
15 |
54295026 (+) |
C |
13% |
39 |
5% |
(1/20) |
6. |
Ube2l3* |
16 |
17152203 (-) |
G |
16% |
271 |
45% |
(9/20) |
7. |
Abcc9* |
6 |
142538042 (-) |
G |
14% |
28 |
14% |
(3/22) |
|
Abcc9* |
6 |
142538035 (-) |
G |
11% |
52 |
18% |
(4/22) |
8. |
Aldh6a1 |
12 |
85772761 (-) |
G |
12% |
854 |
14% |
(3/22) |
9. |
Tmem30a |
9 |
79617629 (-) |
G |
11% |
95 |
8% |
(2/23) |
10. |
Mpeg1* |
19 |
12539179 (+) |
C |
11% |
66 |
5% |
(1/21) |
11. |
Usp25 |
16 |
77116537 (+) |
C |
BTa |
12 |
9% |
(2/22) |
12. |
Sh3bgrl |
X |
106355759 (+) |
C |
BTb,c |
49 |
17% |
(3/18) |
13. |
Cmtm6 |
9 |
114658289 (+) |
C |
BTb,c |
147 |
4% |
(1/22) |
14. |
Sep15 |
3 |
144259976 (+) |
C |
BTb |
379 |
19% |
(4/19) |
15. |
Cyp4v3 |
8 |
46391931 (-) |
G |
BTb |
350 |
14% |
(3/22) |
16. |
Rnf128 |
X |
136207009 (+) |
C |
BTb,c |
260 |
32% |
(7/22) |
17. | B2m | 2 | 121978638 (+) | C | BTb | 8013 | 9% | (2/21) |
BT, below threshold.
aLess than three reads supporting C-to-U editing.
bLess than 10% C-to-U editing.
cDoes not have one read per strand.
(+) Sense strand.
(-) Antisense strand.RNAs with asterisk are liver-specific (compare Figure 1).
Remaining RNAs are shared between liver and intestine.