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. 2014 Jun 30;15(6):R88. doi: 10.1186/gb-2014-15-6-r88

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Copyright © 2014 Colonna et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Examples of genomic regions hosting HighD sites. (a) Known examples; (b) novel examples. Comparison with other statistics informative for positive selection is also reported. Dashed vertical grey lines in the plots indicate the position of the HighD site. In the case of DARC, this HighD site corresponds to the known functional polymorphism rs2814778. Dotted horizontal grey lines indicate reference thresholds taken from the literature for statistics for XP-EHH and iHS, or arbitrary for F_ST, and as chosen in this study for ΔDAF.