Figure 5.

Construction of alignment guides from a GHM between two homologous segments. The anchor points 0 to 7 are included in the alignment guide. Anchor points 8, 9, and 10 are not considered because their inclusion makes the alignment guide invalid because of the implicit requirement that every subsequent anchor point must be lower and to the right of the previous one. The values of Δx and Δy (the number of positions between two subsequent anchor points in the alignment guide; see text) have been indicated for anchor points 2 and 3.