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. 2014 Sep 1;28(17):1917–1928. doi: 10.1101/gad.245910.114

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© 2014 Liu et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 6. — Genetic loss of ZBTB7A in multiple types of human cancer. (A) CNV values of ZBTB7A in early stages (N0, M0, and stage I) and late stages (N1, N2, N3, M1, and stage IV) of multiple types of human cancer were downloaded from the TCGA SNP array data set. Average CNV values and associated SEM and P-values are shown. Expression levels of ZBTB7A mRNA (B) and relative copy number variation (CNV) values (C) in human colorectal cancer at M0 (without distant metastasis) or M1 (with distant metastasis) stage are shown. Error bars represent mean ± SEM. (D) Kaplan-Meier overall survival curves of colorectal cancer patients with high or low ZBTB7A mRNA expression. (E) The correlation of mRNA levels of ZBTB7A with GLUT3, PFKP, or PKM in human colorectal cancer.