Table 2.
Codon Changes Due to Coding SNPs Between PGF and COX
| Classical MHC genes | Other genes | Total | |
|---|---|---|---|
| Synonymous | 48 | 78 | 126 |
| Nonsynonymous | |||
| Conservative | 68 | 36 | 104 |
| Nonconservativea | 59 | 31 | 90 |
| Total | 175 | 145 | 320 |
Distribution of the 320 codon changes.
a
Nonconservative variations were defined as amino acid changes that gave a negative score in a BLOSUM 62 matrix. Classical MHC genes include HLA-A, HLA-B, HLA-C, HLA-DRB1, HLA-DRA1, HLA-DQB1, HLA-DQA1, HLA-DPB1, HLA-DPA1; other genes include all other coding genes.