Table 1.
KD of scFvs for biotinylated EGFR ECD and A431 cells
| *KD for biotin-EGFR ECD (μM) | KD for A431 cells (nM) | ||
|---|---|---|---|
| wild type | C10 | N/A | 263.67 |
| primary mutants | P2/1 | 3.2 | 14.81 |
| P2/2 | 1.8 | 17.01 | |
| P2/4 | 1.8 | 15.39 | |
| P3/5 | N/A | 88.24 | |
| combined mutants | 2124 | 0.56 | 9.90 |
| 2224 | 0.6 | 0.94 | |
| 3524 | 1.24 | 7.47 | |
KD was measured on scFv displayed on yeast