Table 2.
Apparent KD of immunoliposomes constructed with wild type and affinity-matured scFv as measured on MDAMB468 cells by flow cytometry.
|
KD (nM) | |||||
|---|---|---|---|---|---|
| scFv/liposome | 12 | 25 | 37 | 74 | 148 |
| C10 | nd | nd | nd | 1.75 | 0.36 |
| P2/4 | nd | nd | 2.04 | 0.4 | 0.18 |
| 2224 | 13364 | 11.76 | 2.08 | 0.34 | 0.22 |
nd = not determinable.