Skip to main content
. 2014 Aug 14;15(9):973–981. doi: 10.15252/embr.201438618

Figure 1. Loss of mtm-3 impairs autophagy.

Figure 1

A-F′ Confocal fluorescent images of wild-type (A, C, E) and mtm-3(tm4475) (B, D, F) embryos at the 1.5-fold stage stained by DAPI (A–F) and anti-SQST-1 (A′, B′), anti-SEPA-1 (C′, D′) or anti-LGG-1 (E′, F′) antibodies. Scale bars: 5 μm.

G Western blot analysis of LGG-1-I and LGG-1–II (lipidated) in wild type, epg-6, and mtm-3.

H mtm-3 and epg-6 mutant L1 larvae have shortened mean and maximum life span in the absence of food. At least 300 animals were scored each day.

Source data are available online for this figure.