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. 2014 Jun 10;33(14):1599–1613. doi: 10.15252/embj.201385965

Figure 4. dMes-4 prone Set-2/Hypb H3K36me3-mediated nucleosome positioning.

Figure 4

  1. Heat map of nucleosome positioning as measured by MNase-Seq along all Drosophila genes ranked according to H3K36me2 levels. Top: highest H3K36me2 levels in wild-type cells. Nucleosomes were aligned relative to TSS (x-axis; position 0) of genes. NFR, Nucleosome Free Region; +1, positioning of the first nucleosome.
  2. Same as in (A) except that genes were ranked according to H3K36me3 levels.
  3. Averaged nucleosome positioning for genes ranked according to quartiles defined by the amount of ChIP-Seq reads of H3K36me2 (from q1/highest to q4/lowest levels; see Materials and Methods). y-axis, number of MNase-Seq reads; x-axis, alignment along the TSS of genes (TSS = position 0).
  4. Same as in (C) except that quartiles were defined according to H3K36me3 levels.