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| Agent | Mechanism of action |
|---|---|
| Vemurafenib, dabrafenib | Inhibition of BRAF |
| Ibrutinib | Bruton’s tyrosine kinase inhibitor |
| Trematinib, selumetinib | MAPK (mitogen activated protein kinase) inhibitors |
| Moxetumomab pasudotox | High-affinity anti-CD22 immunotoxin |
