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. 2014 Oct 15;9(10):e108854. doi: 10.1371/journal.pone.0108854

Table 2. Linkage of trehalose-6-mycolate, phosphatidylinositol and the D-series resolvin metabolite(s) in plasma of patients without or with MDR-TB.

Metabolite feature Non-MDR-TB patientsa b MDR-TB patientsc Household contactsd
Trehalose-6-mycolate 13/14 1/3 1/17
Phosphatidylinositol (PI) 14/14 1/3 1/17
D-series resolvin 12/14 2/3 2/17
a

In all 13 non-MDR-TB patients with detectable trehalose-6-mycolate metabolite in plasma, the phosphatidylinositol metabolite was also detected.

b

In all 12 non-MDR-TB patients with the D-series resolvin(s) metabolite detected in plasma, the trehalose-6-mycolate and PI metabolites were concomitantly detected.

c

One of 3 patients with MDR-TB demonstrated the D-series resolvin(s), trehalose-6-mycolate and PI metabolites in plasma.

d

One of the 17 smear-negative household contacts demonstrated both trehalose-6-mycolate and the PI metabolites in plasma, but these metabolites were undetectable the other household contacts.

The D-series resolvin metabolite(s) was detected in plasma of 2 other household contacts.