Figure 5.

Progesterone treatment promoted the expression of decorin in ovarian endometrioma. (A) DCN mRNA expression in patients with ovarian endometrioma. A total of 50 cases were selected for the study, and RNA was extracted from surgically obtained endometrioma tissue samples from the control group (n=25) and dienogest group (n=25). The mRNA levels of decorin were measured by real-time PCR and normalized to those of GAPDH mRNA. The data were processed by the comparative Ct method and expressed as a fold-increase relative to the basal transcription level in the control. Bars indicate the s.e.m. Significant differences are indicated by an asterisk. *P<0.05 (B) Decorin and MET expression in ovarian endometrioma. Representative examples of immunohistochemical sequential sections stained with decorin and MET among the ovarian endometrioma samples obtained from endometriosis patients who underwent oophorectomy are shown. A representative section from the no-preoperative-treatment control group is on the left, and a representative section from the dienogest preoperative treatment group is on the right. The black filled arrows indicate the epithelial cells and the white filled arrows indicate the stromal cells.