Figure 1. Serum levels of fT3 (A), fT4 (A) and TSH (B) in the different rat groups at different times after the PTU or LT4 treatments and sacrifice.

Data are represented as the mean ± SEM. n = 10 animals for each group. Statistical analysis was performed with two-way ANOVA tests followed by post hoc Tukey's multiple comparison tests. *p<0.001 vs. control; ^# p<0.001 vs. control and reverse; ^$ p<0.001 vs. 7 and 12 weeks reverse and 12 weeks PTU; ^§ p<0.001 vs. 7 and 12 weeks reverse; ⁺ p<0.001 vs. 7 and 12 weeks reverse and 7 weeks PTU.