Table 2.
Clinical manifestations among the prevalent cases of SLE, according to the ACR and rheumatologist case definitions*
| ACR definition |
Rheumatologist definition |
|||||
|---|---|---|---|---|---|---|
| Clinical manifestation | No. (%) of overall group (n = 2,139) | No. (%) of black cases (n = 1,215) | No. (%) of white cases (n = 820) | No. (%) of overall group (n = 1,909) | No. (%) of black cases (n = 1,146) | No. (%) of white cases (n = 675) |
| Malar rash | 1,055 (49.3) | 520 (42.7) | 483 (58.9)† | 923 (48.4) | 482 (42.2) | 397 (58.5)† |
| Discoid rash | 520 (24.3) | 392 (32.2)† | 111 (13.5) | 456 (23.9) | 350 (30.7)† | 93 (13.7) |
| Photosensitivity | 1,036 (48.4) | 505 (41.4) | 483 (58.9)† | 850 (44.5) | 442 (38.7) | 370 (54.5)† |
| Oral ulcers | 892 (41.7) | 462 (37.9) | 395 (48.2)† | 726 (38.0) | 405 (35.5) | 295 (43.5)† |
| Arthritis | 1,514 (70.8) | 875 (71.8) | 570 (69.5) | 1,314 (68.8) | 793 (69.4) | 461 (67.9) |
| Serositis | 938 (43.9) | 559 (45.9) | 347 (42.3) | 837 (43.8) | 522 (45.7) | 288 (42.4) |
| Renal disorder | 682 (31.9) | 494 (40.5)† | 154 (18.8) | 671 (35.2) | 495 (43.4)† | 145 (21.4) |
| ESRD | 231 (10.8) | 187 (15.3)† | 37 (4.5) | 254 (13.3) | 204 (17.9)† | 42 (6.2) |
| Neurologic disorder | 394 (18.4) | 265 (21.7)† | 115 (14.0) | 354 (18.5) | 243 (21.3)† | 99 (14.6) |
| Hematologic disorder | 1,411 (66.0) | 814 (66.8) | 529 (64.5) | 1,247 (65.3) | 737 (64.5) | 453 (66.7) |
| Immunologic disorder | 1,436 (67.1) | 864 (71.0)† | 503 (61.3) | 1,372 (71.9) | 841 (73.6)† | 462 (68.0) |
| Antinuclear antibody | 2,012 (94.1) | 1,172 (96.1)† | 750 (91.5) | 1,818 (95.2) | 1,102(96.5)† | 635 (93.5) |
Prevalent cases consisted of both new (incident) and existing cases of systemic lupus erythematosus (SLE) during the years 2002–2004. Clinical manifestations consisted of the 11 American College of Rheumatology (ACR) criteria for SLE plus end-stage renal disease (ESRD). The overall group represents the entire population, including persons whose race/ethnicity was not known. The numerator for this category is larger than the sum of the individual subsets, since it includes persons of other racial/ethnic classifications.
Significantly higher proportion of cases with the clinical manifestation between the black and white subgroups.