Table 2. List of mitochondria-derived nuclear genes involved in eukaryotic lipid metabolism.
Gene family | COG | Description | Lipidmetabolized | Cellularlocalization | Identified in Gabaldonet al. 2007 |
Group_236 | COG2867 | cyclase/dehydrase | Oligoketide | Unknown | N |
Group_267 | COG1215 | ceramide glucosyltransferase | Sphingolipid | ER (MAM) | Y |
Group_268 | COG1562 | squalene/phytoene synthase | Cholesterol | ER | Y |
Group_946 | COG1154 | 1-deoxy-D-xylulose-5-phosphate synthase | Terpernoid | ER | Y |
Group_1713 | COG3660 | hypothetical protein | Likely lipid A | Mitochondria | Y |
Group_1971 | COG5597 | sqdD glycosyl transferase | Sulfolipid | Unknown | N |
Group_2416 | COG1044 | lpxD UDP-3-O- 3-hydroxymyristoyl glucosamine N-acyltransferase | Lipid A | Mitochondria | N |
Group_2710 | COG4689 | acetoacetate decarboxylase | Ketone body | Unknown | N |
Group_3620 | COG1043 | lpxA UDP-N-acetylglucosamine acyltransferase | Lipid A | Mitochondria | N |
Group_3864 | COG3000 | Sterol C5 desaturase | Sterol | ER | N |
Group_4604 | COG1519 | kdtA 3-deoxy-D-manno-octulosonic-acid transferase | Lipid A | Mitochondria | Y |
Group_4794 | COG0763 | lpxB lipid-A-disaccharide synthase | Lipid A | Mitochondria | N |