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. 2014 Oct 15;9(10):e110685. doi: 10.1371/journal.pone.0110685

Table 2. List of mitochondria-derived nuclear genes involved in eukaryotic lipid metabolism.

Gene family COG Description Lipidmetabolized Cellularlocalization Identified in Gabaldonet al. 2007
Group_236 COG2867 cyclase/dehydrase Oligoketide Unknown N
Group_267 COG1215 ceramide glucosyltransferase Sphingolipid ER (MAM) Y
Group_268 COG1562 squalene/phytoene synthase Cholesterol ER Y
Group_946 COG1154 1-deoxy-D-xylulose-5-phosphate synthase Terpernoid ER Y
Group_1713 COG3660 hypothetical protein Likely lipid A Mitochondria Y
Group_1971 COG5597 sqdD glycosyl transferase Sulfolipid Unknown N
Group_2416 COG1044 lpxD UDP-3-O- 3-hydroxymyristoyl glucosamine N-acyltransferase Lipid A Mitochondria N
Group_2710 COG4689 acetoacetate decarboxylase Ketone body Unknown N
Group_3620 COG1043 lpxA UDP-N-acetylglucosamine acyltransferase Lipid A Mitochondria N
Group_3864 COG3000 Sterol C5 desaturase Sterol ER N
Group_4604 COG1519 kdtA 3-deoxy-D-manno-octulosonic-acid transferase Lipid A Mitochondria Y
Group_4794 COG0763 lpxB lipid-A-disaccharide synthase Lipid A Mitochondria N