Table 3.
Representative apoptosis related genes regulated by rapamycin
| Gene | Fold Change | Type(s) | Location | Entrez Gene Name |
|---|---|---|---|---|
| CDKN1A | -2.649 | Kinase | Nucleus | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CSF1 | 4.473 | Cytokine | Extracellular Space | Colony stimulating factor 1 (macrophage) |
| DAP | -1.642 | Transcription regulator | Cytoplasm | Death-associated protein |
| DDIT4 | -1.775 | Other | Cytoplasm | DNA-damage-inducible transcript 4 |
| EIF4EBP1 | -2.261 | Translation regulator | Cytoplasm | Eukaryotic translation initiation factor 4E binding protein 1 |
| GRIN1 | -8.378 | Ion channel | Plasma Membrane | Glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GZMA | -4.380 | Peptidase | Cytoplasm | Granzyme A (granzyme 1, cytotoxic T-lymphocyte-Gssociated serine esterase 3) |
| C3 | -6.671 | Ehemical - endogenous mammalian | unknown | |
| NOTCH3 | -3.219 | Transcription regulator | Plasma Membrane | Notch 3 |
| NUPR1 | -5.601 | Transcription regulator | Nucleus | Nuclear protein, transcriptional regulator, 1 |
| PERP | -2.031 | Other | Plasma Membrane | PERP, TP53 apoptosis effector |
| PRF1 | -1.976 | Other | Cytoplasm | Perforin 1 (pore forming protein) |
| TGFB3 | -3.483 | Growth factor | Extracellular Space | Transforming growth factor, beta 3 |
| TIMP3 | 3.947 | Other | Extracellular Space | TIMP metallopeptidase inhibitor 3 |