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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Immunogenetics. 2014 Sep 2;66(11):635–649. doi: 10.1007/s00251-014-0799-9

Fig. 4. Variability in immunoglobulin amino acid sequence in equine fetus and adult horse primary lymphoid tissues.

Fig. 4

Heavy and light chain Ig variable region nucleotide sequences, and their respective translated amino acid sequences were obtained from equine fetal (liver and bone marrow) and adult horse (bone marrow) whole tissues. Amino acid variability at each residue of the Ig variable region was calculated as describe by Wu and Kabat (1970) for (a) fetal liver heavy chain, (b) fetal bone marrow heavy chain, (c) adult horse bone marrow heavy chain, (d) fetal liver lambda light chain, (e) fetal bone marrow lambda light chain, and (f) adult horse bone marrow lambda light chain. The three CDR regions are underlined bellow the X-axis.