Table 1.
IFM I | IFM II | HOVON | Mulligan et al. | |
---|---|---|---|---|
Study | IFM 2005# | IFM 2005# | HOVON 65 MM / GMMG HD4$ |
APEX / SUMMIT |
Number of Samples | 136 | 67 | 282 | 162 |
Platform | Affymetrix Exon 1.0 ST array | Affymetrix Exon 1.0 ST array | Affymetrix U133 Plus 2.0 array | Affymetrix U133 Plus 2.0 array |
Patient Population | Newly-diagnosed | Newly-diagnosed | Newly-diagnosed | Relapsed |
Treatment Protocol | VAD, ASCT | Bortezomib, ASCT | VAD/PAD, ASCT | Bortezomib |
Time of Response Measurement | Post-transplant | Post-Induction | Post-transplant | Post Salvage therapy |
Complete response | 44 (32%) | 24 (36 % %) | 76 (27 %) | 73 (43%)∞ |