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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Leukemia. 2014 Apr 15;28(11):2229–2234. doi: 10.1038/leu.2014.140

Table 1.

Characteristics and details of studies used for gene expression profile-based response prediction.

IFM I IFM II HOVON Mulligan et al.
Study IFM 2005# IFM 2005# HOVON 65
MM / GMMG
HD4$
APEX /
SUMMIT
Number of Samples 136 67 282 162
Platform Affymetrix Exon 1.0 ST array Affymetrix Exon 1.0 ST array Affymetrix U133 Plus 2.0 array Affymetrix U133 Plus 2.0 array
Patient Population Newly-diagnosed Newly-diagnosed Newly-diagnosed Relapsed
Treatment Protocol VAD, ASCT Bortezomib, ASCT VAD/PAD, ASCT Bortezomib
Time of Response Measurement Post-transplant Post-Induction Post-transplant Post Salvage therapy
Complete response 44 (32%) 24 (36 % %) 76 (27 %) 73 (43%)
#

: NCBI GEO accession IDs: IFM I: GSE39754, IFM II: GSE55145.

$

: Broyl A, et al. Blood 2010

: Includes patients with partial response; 13 patients with CR and 60 with PR.