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The numbers of mice used for the therapeutic study. Mice were subjected to rAAV9 or PBS injections at 10 months of age and terminated at 15 months
|
Number of mice subjected to AAV injection |
Number of mice that survived and were examined |
Number of mice that died during treatment |
||||
|---|---|---|---|---|---|---|
| PBS | IgVL5D3 | PBS | IgVL5D3 | PBS | IgVL5D3 | |
| TgAPPswe/PS1dE male | 5 | 5 | 5 | 4 | 0 | 1 |
| TgAPPswe/PS1dE female | 3 | 2 | 3 | 1 | 0 | 1 |
| Non-Tg male | 5 | 7 | 4 | 7 | 1 | 0 |
| Non-Tg female | 3 | 4 | 3 | 3 | 0 | 1 |
