Table 2.
Descriptive statistics of the a priori considered predictors by tumour type in pooled dataset (n=5909). Values are numbers (percentages) unless stated otherwise
| Variables | Benign (n=3980) | Borderline (n=339) | Stage I (n=356) | Stage II-IV (n=988) | Metastatic (n=246) |
|---|---|---|---|---|---|
| Median (interquartile range) age (years) | 42 (32-54) | 49 (36-62) | 54 (44-64) | 59 (50-67) | 57 (47-68) |
| Median (interquartile range) serum CA-125 (U/mL)* | 18 (11-39) | 30 (16-86) | 51 (20-195) | 442 (145-1238) | 91 (29-271) |
| Family history of ovarian cancer | 79 (2.0) | 10 (3.0) | 13 (3.7) | 57 (5.8) | 5 (2.0) |
| Median (interquartile range) maximal diameter of lesion (mm) | 63 (45-87) | 86 (51-150) | 106 (71-153) | 85 (56-123) | 86 (56-124) |
| Solid tissue: | |||||
| Presence of solid tissue | 1322 (33.2) | 267 (78.8) | 328 (92.1) | 968 (98.0) | 234 (95.1) |
| Median (interquartile range) proportion solid tissue if present (%) | 42 (20-100) | 37 (24-59) | 61 (38-100) | 100 (56-100) | 100 (64-100) |
| No of papillary projections: | |||||
| 0 | 3424 (86.0) | 135 (39.8) | 227 (63.8) | 772 (78.1) | 213 (86.6) |
| 1 | 333 (8.4) | 69 (20.4) | 25 (7.0) | 56 (5.7) | 12 (4.9) |
| 2 | 80 (2.0) | 21 (6.2) | 17 (4.8) | 30 (3.0) | 0 (0) |
| 3 | 66 (1.7) | 24 (7.1) | 17 (4.8) | 28 (2.8) | 2 (0.8) |
| >3 | 77 (1.9) | 90 (26.5) | 70 (19.7) | 102 (10.3) | 19 (7.7) |
| >10 cyst locules | 199 (5.0) | 74 (21.8) | 69 (19.4) | 93 (9.4) | 36 (14.6) |
| Acoustic shadows | 676 (17.0) | 8 (2.4) | 18 (5.1) | 30 (3.0) | 10 (4.1) |
| Ascites | 64 (1.6) | 28 (8.3) | 65 (18.3) | 473 (47.9) | 90 (36.6) |
| Missing values for CA-125 | 1447 (36.4) | 62 (18.3) | 71 (19.9) | 163 (16.5) | 62 (25.2) |
*Results based on multiple imputation of missing values.