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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Contrast Media Mol Imaging. 2014 Apr 25;9(5):355–362. doi: 10.1002/cmmi.1585

Figure 1.

Figure 1

Principle of the NIR dye (schematics) for minimum self-aggregation upon conjugation to proteins. Stacking causes dye self-aggregation, charged ends prevent dye from aggregating.