Table 2.
No. | Protein name | Criterion of abnormality | % of patients |
---|---|---|---|
1 | ABL1(C)* | ≥ 2 + | 56 |
2 | AURKB(C) | ≥ 1 + | 94 |
3 | BCR(C) | ≥ 2 + | 28 |
4 | BRCA1(C) | < 1 + | 28 |
5 | BRCA2(C) | < 2 + | 32 |
6 | BRCA2(N)* | < 1 + | 34 |
7 | CSNK1E(C) | < 2 + | 54 |
8 | CTNNB1(N) | ≥ 1 + | 44 |
9 | MSH2(C) | < 1 + | 8 |
10 | MSH2(N) | < 1 + | 28 |
11 | MYC(N) | ≥ 2 + | 83 |
12 | P53(N) | ≥ 1 + | 78 |
13 | PARP1(N) | ≥ 1 + | 87 |
14 | POLB(N) | ≥ 1 + | 66 |
15 | RAD54B(N) | ≥ 1 + | 82 |
16 | RB1(N) | < 1 + | 24 |
17 | SGK2(C) | < 2 + | 73 |
18 | SKP2(C) | ≥ 2 + | 23 |
19 | WNT5A(C) | ≥ 1 + | 60 |
The notation (C) and (N) represent cytoplasm and nucleus, respectively.