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Single amino acid changes in Pab1p eliminate Pan3p interactions
| PAB1 allele | 3-AT resistance (mM) upon interaction with Pan3p-FL |
|---|---|
| PAB1 WTa | 60 |
| pab1 506 (R→G) | 0 |
| pab1 510 (G→R) | 0 |
| pab1 514 (Y→C) | 20 |
| pab1 528 (G→D) | 0 |
| pab1 533 (M→T) | 0 |
WT, wild type. Empty vector and PBP1 (357 to 722) produced 0 and 100 mM 3-AT resistance, respectively, for all alleles.
