Table 3.
Statistical analysis for polymorphic SNPs.
| Gene | χ 2 (df = 2) | P value | Fischer's exact | OR | CI |
|---|---|---|---|---|---|
| PAI-1 −6754G/5G | 2.01 | 0.36 | 0.76 | 0.92 | 0.62–1.38 |
| PAI-1 −844 G/A | 10.99 | 0.004 | 0.15 | 0.74 | 0.49–1.11 |
| MTHFR 677C/T | 7.7 | 0.02 | 0.12 | 0.63 | 0.35–1.12 |
| MTHFR 1298A/C | 0 | 0 | 0.11 | 0.71 | 0.47–1.08 |
| Fibrinogen-β −455G/A | 6.93 | 0.03 | 0.41 | 0.78 | 0.45–1.34 |
| Fibrinogen-β 148C/T | 1.47 | 0.47 | 0.34 | 0.79 | 0.49–1.25 |
Statistical tests of SNPs in candidate genes. χ 2 test and observed P values show significant difference in MTHFR C677T, PAI −844 G/A, and fibrinogen-β chain −455G/A SNPs (P < 0.05). No SNP showed significant allelic difference between patients and control group (Fisher's exact >0.05). The P value lesser than 0.05 was the criteria for significance for all statistical tests.