Table 2.
Follow- up values | p | ||
---|---|---|---|
Alive | Deceased | ||
(N = 1822) | (N = 95) | ||
Weight (Kg) | 83.8 ± 16.4 | 84.7 ± 17.9 | 0.57 |
BMI (Kg/m 2 ) | 29.8 ± 5.1 | 29.5 ± 4.8 | 0.64 |
Fasting glucose (mg/dl) | 143.3 ± 30.6 | 148.8 ± 36.9 | 0.08 |
HbA 1c (%) | 7.6 ± 1.2 | 7.7 ± 1.3 | 0.22 |
Systolic blood pressure (mmHg) | 136.7 ± 11.9 | 136.1 ± 12.0 | 0.66 |
Diastolic blood pressure (mmHg) | 80.4 ± 5.6 | 79.0 ± 5.2 | 0.01 |
Total cholesterol (mg/dl) | 196.0 ± 36.1 | 197.5 ± 37.1 | 0.71 |
LDL cholesterol (mg/dl) | 113.6 ± 32.2 | 114.8 ± 31.2 | 0.72 |
HDL cholesterol (mg/dl) | 50.5 ± 12.8 | 50.0 ± 13.9 | 0.74 |
Triglycerides (mg/dl)° | 147.0 (108.0-196.0) | 149.5 (115.5-204.0) | 0.52 |
Creatinine (mg/dl)°# | 0.9 (0.8-1.1) | 1.1 (0.9-1.7) | 0.001 |
Complications (%) | |||
- Hypertension | 71.0 | 74.7 | 0.25 |
- Dyslipidaemia | 79.5 | 86.3 | 0.06 |
- Coronary hearth disease | 5.8 | 7.4 | 0.32 |
- Cerebro-vascular disease | 1.3 | 2.1 | 0.35 |
- Peripheral arterial disease | 2.9 | 6.3 | 0.06 |
- Nephropathy | 17.0 | 36.8 | 0.001 |
- Retinopathy | 8.3 | 16.8 | 0.007 |
- Neuropathy | 3.0 | 4.2 | 0.33 |
Treatments (%) | |||
Antihypertensive | 55.8 | 63.2 | 0.09 |
Lipid-lowering | 37.9 | 26.3 | 0.01 |
Antidiabetic | |||
- Only diet | 10.0 | 14.7 | 0.21 |
- Biguanides | 33.5 | 16.8 | 0.001 |
- Sulfonylureas | 4.9 | 3.2 | 0.32 |
- Biguanides + Sulfonylureas | 29.6 | 22.1 | 0.07 |
- Insulin | 7.0 | 23.2 | 0.001 |
- Insulin + OHA | 15.0 | 20.0 | 0.12 |
Mean values were calculated upon all records during follow-up, with a mean number of 10 visits for each patient (range: 6 to 15 visits). The total prevalence of complications and treatments were evaluated at the time of the end of the study.
°Median (interquartile range) # Not available in 552 patients.