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. 2014 Oct 8;11:52. doi: 10.1186/s12989-014-0052-6

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© Silva et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Macrophage clearance of Ag NW. Graph shows absolute numbers of macrophages (left), and silver-positive macrophages (right) in BALF on Days 1-21 post IT of S-Ag NWs (A-B), or L-Ag NWs (C-D). Results are from ANOVA considering dose, time, and particle length at p < 0.05. “d” indicates a significant difference from sham control group (in the same panel, sacrificed on the same day). “t” indicates a significant difference between animals (in the same panel, given the same treatment), but sacrificed on Day 1 versus Day 7.