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Sequence analysis of ORF5 alleles of HVS. Amino acid sequences of ORF5 proteins from 13 different isolates of HVS were aligned by using the Cluster W program. Sequences are grouped into three clusters: the A11 cluster of HVS subgroup A (light gray), the OMI cluster of subgroup A (gray), and HVS subgroup C (dark gray). The putative myristoylation at the second glycine residue is indicated by asterisks, and the six potential SH2 binding motifs are underlined.
