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. Author manuscript; available in PMC: 2014 Oct 16.
Published in final edited form as: Expert Rev Clin Pharmacol. 2013 May;6(3):249–269. doi: 10.1586/ecp.13.18

Table 3.

Symptoms of Opioid Withdrawal and Excess [208]

Opioid Withdrawal Subjective:

  • Craving for opioids

  • Irritability

  • Myalgias

  • GI: nausea, vomiting and diarrhea

  • Muscle spasms

  • Flushing

  • Abdominal pain


Objective:

  • Restlessness

  • Diaphoresis

  • Lacrimation

  • Rhinorrhea

  • Mydriasis (dilated pupils)

  • Yawning

  • Piloerection (goose flesh)

  • Tachycardia

  • Tremulousness
Opioid Excess Miosis (pinpoint pupils)
Sedation/Lethargy
Bradycardia
Respiratory depression (shallow and slower respirations)
Hypothermia
Stupor
Coma