Fig. 2.

Effects of RCM extracts on NO production and iNOS expression in LPS induced RAW 264.7. RAW 264.7 cells were treated with UE, UH, RE and RH (400 µg/ml) for 24 h then stimulated with LPS (1 µg/ml) for 4 h (B) or 18 h (A, C). Relative NO production, iNOS mRNA expression and iNOS protein expression were measured by nitrite/nitrate kit (A), PCR (B), and western blot (C). Values not sharing the same letter were significantly different (P < 0.05). (UE: unripe Rubus coreanus Miquel ethanol extract, UH: unripe Rubus coreanus Miquel water extract, RE: ripe Rubus coreanus Miquel ethanol extract, and RH: ripe Rubus coreanus Miquel water extract)