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. 2014 Aug 26;11(9):8709–8742. doi: 10.3390/ijerph110908709

Figure 1.

Taxonomy of the nuclear receptor (NR) superfamily and members of the families 1-6 (NR1-6).

Figure 1

NR1 consists of TR: thyroid receptor; RAR: retinoic acid receptor; PPAR: peroxisome proliferator-activated receptor; ROR: retinoic acid related orphan nuclear receptor; LXR: liver X receptor; FXR: farnesoid X receptor; VDR: vitamin D receptor; PXR: pregnane X receptor and CAR: constitutive androstane receptor. Note: no full terminology for Rev-erb. NR2 consists of HNF: hepatocyte nuclear factor; RXR: retinoid X receptor; TR: testicular receptor; TLL: tailless-like receptor; PNR: photoreceptor-specific nuclear receptor; COUP-TF: chicken ovalbumin upstream promoter transcription factor and EAR: ErbA-related protein. NR 3 consists of ER: estrogen receptor; ERR: estrogen-related receptor; GR: glucocorticoid receptor; MR: mineralocorticoid receptor; PR: progesterone receptor and AR: androgen receptor. NR4 consists of NGFI-B: nerve growth factor-induced clone B; NURR: Nur-related factor and NOR: neuron-derived orphan receptor. NR5 consists of SF1: steroidogenic factor 1 and LRH: liver receptor homolog. NR6 consists of GCNF: germ cell nuclear factor; DAX-1: dosage-sensitive sex reversal-adrenal hypoplasia congenital critical region on the X chromosome protein 1 and SHP: small heterodimer partner. Table adapted from [19,20].