Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Sep;141(17):3399–3409. doi: 10.1242/dev.106773

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Fig. 3. — Overexpression of Gαo or Fz2 in the presynaptic cell, as well as downregulation of Sgg, stimulates bouton formation in NMJ. (A) Wild-type NMJ stained for the presynaptic marker Brp (red); the postsynaptic cell is visualized by CD8-GFP-Sh (green). (B,C) Overexpression of Gαo and its mutant GTP-loaded form (Gαo[Q205L]) in the presynaptic cell leads to enhanced bouton formation. (D,E) Overexpression of fz2 or expression of RNAi-sgg produces similar phenotypes. (F) Quantification of bouton numbers in the different genotypes (shown as in Fig. 2A). n.s., not significant (P>0.05). Scale bar: 10 µm.