TABLE 3.
S. enterica serovar Typhimurium genes belonging to the LSMMG regulona
| STM gene ID no. | Gene name | Expression ratiob (mean ± SD) | Gene function(s) |
|---|---|---|---|
| Up-regulated genes | |||
| STM0459 | ybaO | 6.50 ± 3.04 | Putative transcriptional regulator, AsnC family |
| STM1625 | ydcI | 5.00 ± 0 | Putative transcriptional regulator, LysR family |
| STM3014 | lysR | 5.00 ± 4.36 | Positive transcriptional regulator, LysR family |
| STM4322 | yjdC | 8.33 ± 2.89 | Putative bacterial regulatory protein, merR family |
| STM0592 | fepD | 3.17 ± 1.61 | ABC superfamily, ferric enterobactin transporter |
| STM1471 | rstB | 10.00 ± 0 | Sensory histidine kinase, two-component with RstA |
| STM3630 | dppA | 8.33 ± 2.89 | ABC superfamily, dipeptide transport protein |
| STM1327 | ydiY | 10.00 ± 0 | Putative salt-induced outer membrane protein |
| STM1517 | ydeD | 7.33 ± 4.62 | Putative permease, integral membrane protein |
| STM4591 | sthE | 6.67 ± 2.89 | Putative major fimbrial subunit |
| STM3069 | pgk | 10.00 ± 0 | Phosphoglycerate kinase |
| STM3939 | cyaA | 5.73 ± 3.96 | Adenylate cyclase |
| Down-regulated genes | |||
| STM2869 | orgA | 0.26 ± 0.04 | SPI-1 type III secretory protein |
| STM2874 | prgH | 0.35 ± 0.11 | SPI-1 type III secretion machinery |
| STM2883 | sipD | 0.37 ± 0.07 | SPI-1 type III secreted protein, regulator of secretion |
| STM2893 | invI | 0.33 ± 0.18 | SPI-1 type III secretory protein |
| STM2896 | invA | 0.35 ± 0.11 | SPI-1 type III secretion machinery |
| STM2902 | pigB | 0.41 ± 0.07 | SPI-1 pathogenicity island-associated protein |
| STM1398 | sseB | 0.42 ± 0.11 | SPI-2 type III secretion system effector |
| STM1412 | ssaL | 0.28 ± 0.11 | SPI-2 type III secretion system apparatus |
| STM1414 | ssaV | 0.35 ± 0.03 | SPI-2 type III secretion system apparatus |
| STM1631 | sseJ | 0.37 ± 0.03 | SPI-2 type III secretion system effector |
| STM0543 | fimA | 0.41 ± 0.1 | Major type I fimbrial subunit |
| STM2082 | rfbP | 0.41 ± 0.08 | LPS side chain synthesis |
| STM2084 | rfbM | 0.42 ± 0.05 | LPS side chain synthesis |
| STM2093 | rfbI | 0.32 ± 0.01 | LPS side chain synthesis |
| STM1371 | sufC | 0.46 ± 0.06 | Putative ABC superfamily transport protein |
| STM1373 | sufS | 0.34 ± 0.06 | Selenocysteine lyase |
a
This list is not comprehensive but is representative of the 163 LSMMG regulon genes identified by microarray analysis.
b
Expression ratio is the value for the LSMMG fluorescent channel divided by the value for the 1 × g channel as described in reference 107.