Table 1.

Characteristics of Women with and without PAD.

Traditional Risk Factors	Women with PAD (n=21)	Women without PAD (n=163)	p-value
Age, Mean (SD), y	67 ± 12	64 ± 11	0.21
Caucasian	11 (52)	80 (49)	0.78
BMI	28 ± 7	30 ± 6	0.39
Waist-hip ratio	0.88± 0.06	0.88 ±0.07	0.86
Comorbidities and Cardiac Disease Severity
Hypertension	16 (76)	120 (74)	0.80
Hx of MI	11 (55)	72 (45)	0.38
Past Coronary Revascularization	9 (43)	72 (44)	0.89
LVEF (%)	64 ± 7	64 ± 8	0.93
CCHF	5 (24)	28 (17)	0.46
Treadmill Score (METs)	6 ± 3	7 ± 3	0.23
Diabetes Mellitus	7 (33)	44 (27)	0.54
Arthritis	15 (71)	100 (62)	0.49
History of Alcoholism	3 (14)	8 (5)	0.01
Systolic Blood Pressure (mm Hg)	139 ± 21	137 ± 22	0.82
Diastolic Blood Pressure (mmHg)	71 ± 11	76 ± 11	0.07
Medications
Aspirin	13 (62)	115 (71)	0.42
ACE-inhibitor	8 (38)	76 (47)	0.46
B-Blocker	8 (38)	87 (53)	0.19
Statin	10 (48)	89 (55)	0.55
Anti-depressant	5 (24)	40 (25)	0.94
Traditional Risk Factors, Inflammation and Metabolic Factors
History of Smoking	12 (57)	90 (55)	0.87
Total Cholesterol	196 ± 52	191 ± 48	0.65
LDL	114 ± 9	111 ± 41	0.78
HDL	53 ± 17	53 ± 17	0.94
Hemoglobin A1c (%)	6 ± 1	6 ± 1	0.48
Glucose (mg/dL)	132 ± 55	116 ± 36	0.07
Log CRP (mg/L)	0.7 ±1.3	1.1 ± 1.3	0.22
Log IL-6 (pg/ml)	1.0 ± 0.6	0.9 ± 0.8	0.31
Log TNF-α (pg/ml)	1.4 ± 1.1	1.2 ± 0.8	0.52
Log fibrinogen (mg/dL)	6.0 ± 0.2	6.0 ± 0.2	0.35
Psychosocial and Behavioral Risk Factors
Depression by PHQ-9 score	10 (48)	37 (23)	0.01
Current PTSD	1 (5)	22 (14)	0.26
History of General Anxiety Disorder	5 (24)	30 (18)	0.55
Anxiety Score	7 ± 3	7 ± 4	0.88
Married	3 (14)	45 (28)	0.19
Poor Social Support	16 (76)	113 (69)	0.52
Physically active	14 (67)	86 (53)	0.24
Adherent to medication	17 (81)	139 (87)	0.41
Regular alcohol use	4 (19)	25 (16)	0.68