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. Author manuscript; available in PMC: 2014 Oct 16.
Published in final edited form as: Ann N Y Acad Sci. 2009 Oct;1178:157–172. doi: 10.1111/j.1749-6632.2009.05002.x

Figure 2.

Figure 2

Representative endogenous Jaagsiekte sheep retrovirus (en-JSRVs) proviruses present within the sheep genome. Five en-JSRVs display an intact genomic organization typical of replication competent proviruses (top). The ″W″ present in the Gag protein of the two transdominant proviruses enJS56A1 and enJSRV-20 indicates the R21W substitution. enJSRV-20 5′ flanking region contains an env gene indicated by a box and a question mark (?). Vertical lines and an asterisk (*) represent stop codons, while hatched boxes indicate deletions. enJSRV-6 harbors a recombined structure with internal sequence in the opposite direction compared to the 5′ and 3′ long terminal repeats of the provirus. The first methionine (indicated by the letter M) of the env gene of enJSRV-6 is present after the usual start codon.