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. 2014 Oct 16;5:399. doi: 10.3389/fphys.2014.00399

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Copyright © 2014 Tong, Ghouri and Taggart.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of reducing I_CaT in uterine and cardiac cells. Effects on the action potential forms and characteristics with reduced I_CaT in different cell types: the USMC cell model (left), the SAN cell model (center), and the LRd00 ventricular cell model (right). (A) Control configuration at full I_CaT and the effects of reducing I_CaT by: (B) 40%, (C) 80%, and (D) 100%. The negative sign indicated reduction.