Figure 5.

Stimulating anesthetized rats results in cortical and hippocampal activation. For example, testing the rats righting reflex (arrow in top record) stimulates vestibular, proprioceptive, and other sensory inputs—resulting in an awake-like “activated” EEG signal. Activation occurred regardless of whether righting was lost or not, and rapidly retuned to a slow wave “delta” pattern seconds after the stimulus onset, regardless of whether the rat righted itself or not. In the middle recordings, the righting reflex was tested 1 s before the start of the recording, and an activated EEG pattern was seen for the entire recording shown (7.0 s), even though the rat failed to right itself. In the lower recording, the EEG is seen to return to slow wave activity within 10 s, and the slow wave activity in cortex appeared to be synchronized with LIA hippocampus. Calibration = 300 μV and 1.0 s.