Table 2.
Summary of the genes analyzed in this study
| Gene | Full name of the protein | Synonyms | Site of expression/function | EP | SVA/WB | IHC |
|---|---|---|---|---|---|---|
| MYH1 | Myosin heavy chain (MHC) 1 | Myosin-1; MyHC-IIx | Adult skeletal fast type 2B | X | ||
| MYH2 | Myosin heavy chain 2 | Myosin-2, MyHC-IIa | Adult skeletal fast type 2A | X | X | |
| MYH3 | Myosin heavy chain 3 | Myosin-3; MyHC-emb | Embryonic/fetal and regenerating muscle | X | X | |
| MYH4 | Myosin heavy chain 4 | Myosin-4; MyHC-IIb | Adult skeletal muscle (masseter and abdominal external oblique only) | X | (X) | |
| MYH6 | Myosin heavy chain 6 | Myosin-6; MyHC-alpha | Heart | X | ||
| MYH7 | Myosin heavy chain 7 | Myosin-7; MyHC-beta/slow | Adult skeletal slow type 1 fibers; heart | X | X | |
| MYH7B | Myosin heavy chain 7B | Myosin-7B; myosin cardiac muscle beta chain | Heart | X | ||
| MYH8 | Myosin heavy chain 8 | Myosin-8; MyHC-pn | Perinatal/neonatal and reprogramed/regenerating muscle | X | X | |
| MYH10 | Myosin heavy chain 10 | Myosin-10; non-muscle II-b; NMMHC II-b | Brain | X | ||
| MYH13 | Myosin heavy chain 13 | Myosin-13; MyHC-eo | Skeletal muscle, extraocular | X | ||
| LDB3 | LIM domain-binding protein 3 | Z-disk alternatively spliced PDZ-motif protein, ZASP | Sarcomeric Z-disk | X | ||
| TNNT3 | Troponin T, fast skeletal muscle | fTnT | Preferentially adult skeletal fast type 2 fibers | X | X | X |
| CALML6 | Calmodulin-like protein 6 | Calglandulin-like protein | Ca2+ signalling | X | ||
| CAMKK2 | Ca2+/calmodulin dependent protein kinase kinase 2 | CaMKK beta | Ca2+ signalling | X | ||
| MEF2A | Myocyte-specific enhancer factor 2A | Serum response factor-like protein 1 | Transcription factor, muscle-specific | X | ||
| MEF2B | Myocyte-specific enhancer factor 2B | Serum response factor-like protein 2; XMEF2 | Transcription factor, muscle-specific | X | ||
| MEF2C | Myocyte-specific enhancer factor 2C | Transcription factor, muscle-specific | X | |||
| MYOD1 | Myoblast determination protein 1 | Myogenic factor 3, Myf-3 | Muscle differentiation | X | ||
| MYF5 | Myogenic factor 5 | Myf-5 | Muscle differentiation | X | ||
| NFATC4 | Nuclear factor of activated T-cells, cytoplasmic 4 | T-cell transcription factor NFAT3 | Transcription factor | X | ||
| MYF6 | Myogenic factor 6 | Muscle-specific regulatory factor 4, MRF4 | Muscle differentiation | X | ||
| SIX1 | Homeobox protein SIX1 | Sine oculis homeobox homolog 1 | Transcription factor, muscle-specific | X | ||
| TEAD4 | Transcriptional enhancer factor TEF-3 | TEA domain family member 4, TEAD-4; RTEF-1 | Transcription factor (preferentially in muscle) | X | ||
| NCAM1 | Neural cell adhesion molecule 1 | NCAM-1; CD56 | Membrane protein; (neural) adhesion | X | ||
| MYOG | Myogenin | Myogenic factor 4, Myf-4 | Muscle differentiation | X | X | |
| VIM | Vimentin | Class III intermediate filament; developing/regenerating muscle | X |
EP expression profiling; SVA splice variant analysis; WB western blotting; IHC immunohistochemistry