Table I.
Dynamic alterations of the biochemical indices in the infant with citrin deficiency.
| Biochemical indices | 3.3 M | 3.5 M | 4.0 M | 4.3 M | 4.5 Ma | 4.6 M | 4.7 M | 4.8 M | 5.0 M | 5.5 M | 5.8 M | 7.0 Mb | 11 M |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALT (5–40 U/l) | 49 | 44 | 100 | 138 | 198 | 99 | 137 | 83 | 58 | 40 | 55 | 36 | 27 |
| AST (5–40 U/l) | 66 | 58 | 88 | 118 | 124 | 75 | 113 | 62 | 50 | 37 | 67 | 37 | 45 |
| GGT (8–50 U/l) | 444 | 411 | 537 | 532 | 388 | 313 | 465 | 508 | - | 364 | 134 | 318 | 34 |
| ALP (20–500 U/l) | 618 | 588 | 1133 | 1209 | 1332 | 1011 | 1428 | 944 | 643 | 174 | 426 | 420 | 399 |
| TP (60.0–83.0 g/l) | 56.9 | 54.9 | 61.2 | 56.1 | 50.0 | 56.8 | 60.8 | 68.5 | 73.5 | - | 61.6 | 68.7 | 68.6 |
| Alb (35.0–55.0 g/l) | 40.2 | 39.7 | 41.7 | 39.4 | 34.6 | 40.5 | 43.5 | 45.4 | 49.0 | - | 45.5 | 50.0 | 51.1 |
| Glb (20.0–30.0 g/l) | 16.7 | 15.2 | 19.5 | 16.7 | 15.4 | 16.3 | 17.3 | 23.1 | 24.5 | - | 16.1 | 18.7 | 17.5 |
| Tbil (2–19 μmol/l) | 67.7 | 59.2 | 123.6 | 149.8 | 204.5 | 148.3 | 135.9 | 67.3 | 45.4 | 20.3 | 13.2 | 3.9 | 5.5 |
| Dbil (0–6 μmol/l) | 53.8 | 48.7 | 96.3 | 118.4 | 161.6 | 120.1 | 110.8 | 57.4 | 40.1 | 13.0 | 9.4 | 1.8 | 1.4 |
| Ibil (2.56–20.9 μmol/l) | 13.9 | 10.5 | 27.3 | 31.4 | 42.9 | 28.2 | 25.1 | 9.9 | 5.3 | 7.3 | 3.8 | 2.1 | 4.1 |
| TBA (0–10 μmol/l) | 157.5 | 152.8 | 135.1 | 112.3 | 173.3 | 26.6 | 26.9 | 5.5 | 4.7 | 49.33 | 8.7 | 7.3 | 2.1 |
M, months (age of infant).
a
Time at which laparoscopic surgery was performed, and
b
time of referral to our hospital.
ALT, alanine transaminase; AST, aspartate transaminase; GGT, gamma-glutamyl transpeptidase; ALP, alkaline phosphatase; TP, total protein; Alb, albumin; Glb, globulin; Tbil, total bilirubin; Dbil, direct bilirubin; Ibil, indirect bilirubin; TBA, total bile acid.