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. 2014 Sep 5;10(5):2255–2262. doi: 10.3892/mmr.2014.2544

Figure 1.

Figure 1

Effect of taurine on hepatocyte apoptosis in iron-overloaded mice. TUNEL-positive cells were apoptotic. (A–D) Liver sections from the different treatment groups: (A) placebo + vehicle, (B) placebo + taurine, (C) iron + vehicle and (D) iron + taurine (magnification, ×400). (E) Quantitative analysis of hepatocyte apoptosis expressed as the percentage of TUNEL-positive nuclei among the hepatocytes. Data are presented as the mean ± standard error of the mean (n=12). aP>0.05 vs. the placebo + vehicle group; bP<0.01 vs. the placebo + vehicle and placebo + taurine groups and cP<0.01 vs. the iron + vehicle group. TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling.