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. 2014 Aug 12;34(5):1195–1200. doi: 10.3892/ijmm.2014.1895

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Copyright © 2014, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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(A) Immunohistochemical staining with a DEPTOR antibody revealed a reduction in its expression in the precentral gyrus, postcentral gyrus and occipital lobe of a brain with Alzheimer’s disease (AD) compared to a healthy control brain. (B) DEPTOR expression levels in human late onset AD (LOAD) samples were significantly reduced compared to early onset familial AD (EOFAD) samples. Data are the means ± standard error of the mean (SEM). ^*P<0.05, stastistically significant difference between LOAD and EOFAD (n=5).

(A) Immunohistochemical staining with a DEPTOR antibody revealed a reduction in its expression in the precentral gyrus, postcentral gyrus and occipital lobe of a brain with Alzheimer’s disease (AD) compared to a healthy control brain. (B) DEPTOR expression levels in human late onset AD (LOAD) samples were significantly reduced compared to early onset familial AD (EOFAD) samples. Data are the means ± standard error of the mean (SEM). ^*P<0.05, stastistically significant difference between LOAD and EOFAD (n=5).