Table 2. Single gene/multiple phenotype association.
| Gene | Entrez gene# | CCA p-value | Fisher p-value | Phenotypes |
| ABO | 28 | 3.47E-147 | 1.53E-194 | Creatinine (0.2771) ALP (4.35e-12) FVIII (2.288e-77) Tissue plasminogen activator (0.002849) Von Willebrand Factor (9.43e-112) |
| F7 | 2155 | 4.42E-114 | 7.27E-078 | Cholesterol (0.9719) HDL cholesterol (0.1073) FVII (1.486e-79) FIX (0.5965) |
| F10 | 2159 | 3.58E-079 | 1.61E-059 | Cholesterol (0.8131) FVII (1.24e-60) FIX (0.8744) |
| SURF4 | 6836 | 2.02E-056 | 1.98E-066 | Mean cell volume (0.01924) ALP (3.104e-09) GGT (0.7735) E vitamin_t1 (t1) (0.1303) E vitamin_t2 (0.03584) FVIII (1.573e-24) D-dimer (0.4159) Tissue plasminogen activator (0.1705) Von Willebrand Factor (5.655e-37) MMP9 (0.006049) BMI (0.1158) PR interval (0.04652) Cornell index (0.001895) |
| NRG1 | 3084 | 1.03E-028 | 4.73E-019 | Urea (0.005643) beta-carotene (0.001871) fibrinogen (0.007379) QRS duration (0.0008578) Cornell index (0.651) Cornell product (2.709e-14) |
| HRG | 3273 | 8.02E-024 | 1.03E-022 | Haematocrit (0.05769) Total protein (0.007418) FIX (0.3289) APTT (2.342e-12) Ratio APC/APTT (2.555e-12) |
| IL18 RAP | 8807 | 5.07E-021 | 1.52E-017 | White blood count (0.1395) Haematocrit (0.04132) Neutrophils (0.4115) Lymphocytes (0.831) ALT (0.0287) Glucose (0.06899) FIX (0.03512) Cornell index (0.4867) Cornell product (1.072e-08) Sokolowlyn index (0.2884) QRS voltage product (1.723e-10) |
| CETP | 1071 | 3.65E-020 | 5.94E-020 | HBA1C (0.01231) HDL cholesterol (2.552e-17) Glucose (0.06243) FVII (0.0178) Von Willebrand Factor (0.003123) CD40 (0.01286) |
| ALOX5AP | 241 | 3.49E-018 | 7.28E-011 | White blood count (0.2124) Mean cell volume (0.004036) Neutrophils (0.007984) Urate (0.02255) Phosphate (0.07024) Total protein (0.002632) C Vitamin (0.06383) Tissue plasminogen activator (0.06189) CD40 (0.02214) BMI (0.03787) Height (0.002794) QTC interval (0.08854) Cornell index (0.1151) QRS voltage sum (0.2935) QRS voltage prod (0.08101) |
| IL23R | 149233 | 2.19E-018 | 1.09E-012 | Adiponectin (0.04484) IL18 (0.01227) QRS duration (0.1137) Cornell index (0.2268) Cornell product (3.299e-12) |
| GPR98 | 84059 | 3.37E-008 | 1.31E-006 | White blood count (0.005413) Mean platelet volume (0.1353) Lymphocytes (0.2363) Potassium (0.08101) Sodium (0.05957) Total protein (0.02314) E vitamin (0.03851) Insulin (0.05201) Adiponectin (0.1668) TNFA (0.2093) homa-score (0.2542) CVD (0.02455) |
This table shows single gene/multiple phenotype association. The first column represents the gene, the second column represents the CCA association value, the third column is the Fisher's combined association value and the fourth column the phenotypes associated. In parentheses is the single phenotype association value of each phenotype.