Table 1.
Genotype | Assay1 | Mean Survival2 | S.D.2 | Extension of Survival (%)2 | N3 | Independent Experiments Performed3 | Figure1 |
WT | Heat Stress | 13.4 (hrs) | 2.3 | - | 58 | 2 | 5a,7b |
natc-1(am138) | Heat Stress | 15.9* (hrs) | 2.1 | 19 | 59 | 2 | 5a,7b |
daf-16(mu86) | Heat Stress | 12.7 (hrs) | 2.4 | −5 | 64 | 2 | 7b |
daf-16(mu86); natc-1(am138) | Heat Stress | 15.6* (hrs) | 3.1 | 16 | 56 | 2 | 7b |
WT | Oxidative Stress | 51.6 (hrs) | 19.3 | - | 54 | 4 | 5b |
natc-1(am138) | Oxidative Stress | 72.3* (hrs) | 27.8 | 40 | 88 | 4 | 5b |
WT | Lifespan | 15.9 (days) | 3.7 | - | 254 | 6 | 5c, S5 |
natc-1(am138) | Lifespan | 11.0* (days) | 2.6 | −31 | 230 | 6 | 5c, S5 |
daf-2(e1370) | Lifespan | 34.2* (days) | 9.9 | 116 | 239 | 6 | S5 |
daf-2(e1370); natc-1(am138) | Lifespan | 34.1 (days) | 11.5 | 115 | 244 | 6 | S5 |
Assay, Figure. Animals were analyzed in standard culture conditions (lifespan) or at 35°C (heat stress) or with 40 mM paraquat (oxidative stress). Data are illustrated in the corresponding Figures.
Mean survival, S.D., Extension of Survival. Survival times are presented in hours or days with standard deviation (S.D.). Significant differences are indicated (*, p<0.05). natc-1, daf-16, and daf-2 are compared to WT, daf-16;natc-1 is compared to daf-16, and daf-2;natc-1 is compared to daf-2. Percent extension is compared to WT and can be positive (longer) or negative (shorter).
N, independent experiments performed. The total number of animals analyzed and the number of independent experiments performed.