TABLE 6.
Putative regions of duplication in pathogenic strains detected by CGH microarray analysis
| Position | ORFa | Strain | Ratiob | Characteristic genec | Function |
|---|---|---|---|---|---|
| Start | JW0276 (b0282) | EPEC-1 | 33/36 | eaeH | Attaching and effacing protein homolog |
| End | JW0318 (b0326) | bct genes | Choline/betaine transport and metabolism | ||
| ykgM | Ribosomal protein L31P homologue | ||||
| Start | JW2392 (b2395) | EPEC-4 | 65/73 | gltX | Glutamyl-tRNA synthetase |
| End | JW2465 (b2480) | lig | NAD-dependent DNA ligase | ||
| zipA | Cell division protein ZipA | ||||
| acrD | Acriflavin resistance protein D | ||||
| pts genes | Glucose phosphotransferase system | ||||
| Start | JW3041 (b3070) | EPEC-7 | 41/45 | aer | Aerotaxis receptor |
| End | JW3086 (b3115) | ||||
| Start | JW3451 (b3484) | EPEC-4 | 77/102 | glySQ | Glycyl-tRNA synthetase |
| End | JW3564 (b3591) | aldB | Aldehyde dehydrogenase B | ||
| Start | JW3489 (b3521) | EPEC-5 | 35/35 | cspA | Cold shock protein |
| End | JW3532 (no counterpart) | glySQ | Glycyl-tRNA synthetase | ||
| Start | JW3552 (b3580) | EPEC-2 | 10/10 | aldB | Aldehyde dehydrogenase B |
| End | JW3561 (b3588) |
a
Regions in which more than 10 ORFs were supposed to be successively duplicated. The corresponding b numbers are indicated in parentheses (2).
b
Number of putative duplicated ORFs/number of ORFs in the region.
c
Essential genes that were supposed to be duplicated are indicated by boldface type.