Table 4.

REVEAL registry PAH risk score calculator

Group 1, subgroup	Associated with CTD: +1	Associated with portal hypertension: +2	Heritable: +2
Demographics and comorbidities	Renal insufficiency: +1	Males, age >60 years: +2
WHO functional class	Class 1: -2	Class III: +1	Class IV: +2
Vital signs	Systolic BP <110 mmHg: +1	Heart rate <92 bpm: +1
6-minute walking distance	≥440 m: -1	<165 m: +1
BNP	<50 pg/mL: -2	>180 pg/mL: +1
Echocardiogram	Pericardial effusion: +1
Pulmonary function test	DLCO ≥80% pred: -1	DLCO ≤32% pred: +1
RHC	mRAP >20 mmHg within 1 year: +1	PVR >32 Wood units: +2
		Sum of above +6 = total risk score

Note: Calculated risk scores range from 0 (lowest risk) to 22 (highest risk).

Abbreviations: REVEAL, Registry to Evaluate Early and Long-Term PAH Disease Management; PAH, pulmonary arterial hypertension; CTD, connective tissue diseases; WHO, World Health Organization; BP, blood pressure; BNP, brain natriuretic peptide; DLCO, pulmonary diffusing capacity for carbon monoxide; pred, predicted; RHC, right heart catheterization; mRAP, mean right atrial pressure; PVR, pulmonary vascular resistance.