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. 2014 Oct 16;9(10):e109737. doi: 10.1371/journal.pone.0109737

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© 2014 Uchiyama et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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PK-resistant PrP is detectable with M20 anti-PrP antibodies in all inoculated indicator mice, except for the mice sacrificed at 365 days after inoculation with the brain homogenate from the Tg(MHM2Δ23-88)/Prnp^0/0 mouse, which was sacrificed at 591 days after inoculation with RML prions.