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. 2014 Oct 16;9(10):e110176. doi: 10.1371/journal.pone.0110176

Figure 1. Restricted feeding protocols.

Figure 1

(A) Scheme of the standard RF schedule in which food availability was limited to 4 hours a day (ZT 5–9) from day 1 until day 14. White and black bars represent times of lights on and off, respectively. Gray bars represent times of food availability of either normal chow (NC) or canola oil-enriched chow (COEC). (B) Scheme of the adapted RF schedule in which food availability was gradually decreased during the experiment. Both groups received NC for 8 days (RF group: 1 day 12 h food available (ZT 5–17) and 7 days 9 h food available (ZT 5–14)) and COEC during the remaining 7 days (RF group: 3 days 6 h food available (ZT 5–11) and 4 days 4 h food available (ZT 5–9)). Note that the time of onset of food availability is the same each day (ZT 5).