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. 2014 Oct 16;9(10):e110188. doi: 10.1371/journal.pone.0110188

Table 3. Association between CYP2C19*2, *3, PON1 Q192R and clopidogrel resistance.

CYP2C19*2 (rs4244285)
Genotype Crude OR (95%CI) p-value Adjusted OR (95%CI) p-value
GG (*1/*1) 1 - 1 -
GA (*1/*2) 1.84 (0.99–3.42) 0.053 2.30 (1.14–4.66) 0.021
AA (*2/*2) 12.59 (3.31–47.96) <0.001* 13.23 (2.87–60.88) 0.001*
Allele A (*2) 2.57 (1.59–4.14) <0.001* 2.86 (1.63–5.03) <0.001*

* Risk is statistical significant when compared to the reference genotype at p-value<0.017.

Adjusted for diabetes, age, sex, history of smoking and platelet count.

Adjusted for concurrent *2 or *3 allele and covariates (diabetes, age, sex, history of smoking, and platelet count).